Cannabinoids Beyond THC and CBD
Exploring the Lesser-Known Compounds in Medical Cannabis
Most patients are familiar with THC and CBD, but these are only two of more than 100 cannabinoids found in the cannabis plant. Each has its own potential therapeutic properties, and together they create a more complete and balanced effect through what’s known as the entourage effect.
At Greener Healing Ways, we believe understanding these lesser-known cannabinoids helps patients make more informed choices and discover new possibilities for relief.
🌿 What Are Cannabinoids?
Cannabinoids are active compounds that interact with your body’s endocannabinoid system (ECS) — the network that helps regulate mood, appetite, inflammation, sleep, and pain.
Each cannabinoid has a slightly different structure, meaning it interacts with ECS receptors in unique ways.
Some cause psychoactive effects (like THC), while others do not. Together, they work in harmony to influence the overall therapeutic experience.
🌺 Key Minor Cannabinoids and Their Potential Benefits
CBG (Cannabigerol)
Often called the “mother cannabinoid,” CBG is the chemical precursor from which THC, CBD, and other cannabinoids are formed.
Potential Benefits
Anti-inflammatory and antibacterial properties
May support focus and energy
Shows promise in protecting nerve cells (neuroprotective)
May help regulate bladder function and gut health
CBG is non-intoxicating and may complement CBD for daytime use or focus-based relief.
CBN (Cannabinol)
CBN is a mildly psychoactive compound that forms when THC ages or oxidizes. It is often associated with rest and relaxation.
Potential Benefits
Promotes sleep and relaxation
May enhance pain relief when paired with THC
Potential antibacterial and anti-inflammatory effects
CBN is often included in nighttime tinctures and capsules for its calming effects.
CBC (Cannabichromene)
CBC is a non-psychoactive cannabinoid that appears to boost the effects of other cannabinoids.
Potential Benefits
Anti-inflammatory and analgesic properties
May elevate mood by influencing serotonin
Supports the formation of new brain cells (neurogenesis)
CBC works best as part of a full-spectrum extract, contributing to overall wellness and mental balance.
THCV (Tetrahydrocannabivarin)
THCV is structurally similar to THC but produces very different effects. In small doses, it may reduce appetite and provide mental clarity.
Potential Benefits
Appetite control and weight management
May help balance blood sugar
Promotes alertness and focus
Possible benefits for anxiety and PTSD when combined with CBD
THCV is found in smaller quantities in certain sativa strains and may offer energy-boosting, clear-headed relief for daytime use.
Delta-8 THC and Delta-10 THC
These are natural variations of THC that occur in small amounts. They are psychoactive but typically produce milder effects than Delta-9 THC.
Potential Benefits
Pain and nausea relief
Calmer, more clear-headed experience compared to Delta-9
Useful for patients sensitive to anxiety or paranoia from regular THC
While Delta-8 and Delta-10 products are increasingly available, it’s important to purchase only lab-tested, regulated formulations to ensure purity and safety.
⚖️ How These Cannabinoids Work Together
Each cannabinoid contributes something unique, but their combined action often provides the greatest therapeutic benefit.
For example:
THC + CBD may improve pain control and reduce anxiety.
CBG + CBD may enhance focus while reducing inflammation.
CBN + THC may support deeper, more restorative sleep.
This synergy is the foundation of the entourage effect, where cannabinoids and terpenes amplify one another’s benefits.
💊 Choosing Products Wisely
Many dispensaries now offer products that highlight specific cannabinoids, such as CBG tinctures or CBN sleep gummies. When choosing these, always look for:
Lab testing results for purity and cannabinoid content
Clear labeling showing cannabinoid ratios (e.g., 1:1:1 CBD/CBG/CBN)
Provider guidance to determine whether these are appropriate for your condition
🌈 Key Takeaway
The cannabis plant is far more complex than just THC and CBD. Minor cannabinoids like CBG, CBN, CBC, and THCV offer unique and complementary therapeutic effects that can enhance overall symptom relief.
At Greener Healing Ways, we help patients explore these options safely, tailoring treatment plans that harness the full potential of the cannabis plant — naturally, thoughtfully, and with aloha.
✳️ Next in This Series
[Understanding Tolerance and Dependence]
[Cannabis and Mental Health]
[Cannabinoids and the Immune System]